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Product Profile

Product Name	Anti-BMPR2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	HumanMousePigRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	BMPR2
Gene Synonyms	BMR2 PPH1 BMPR3 BRK-3 POVD1 T-ALK BMPR-II Hide
Gene Full Name	bone morphogenetic protein receptor type 2
Gene Summary	This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020] Hide
Molecular Weight(MW)	115 KDa
Source	Rabbit
Cellular Localizatio	Plasma membrane

Application

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WB

Western blot analysis using BMPR2 antibody against Jurkat (1), A549 (2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded thyroid carcinoma tissues using BMPR2 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.