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    Anti-ATF2 antibody
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM641708
    • 发布日期: 2024-09-10
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM641708
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口

    Product Profile

    Product Name

    Anti-ATF2 antibody

    Antibody Type

    Primary Antibodies

    Immunogen

    Polypeptide

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Application

    ELISAICC/IFIHCWB

    WB:1:200-1:2000
    IHC:1:200-1:2000
    ICC/IF:1:100-1:500

    Species Reactivity

    HumanMouseRat

    Concentration

    1mg/ml

    Purification

    Protein A

    Target Information

    Gene Symbol

    ATF2

    Gene Synonyms

    HB16
    CREB2
    TREB7
    CREB-2
    CRE-BP1

    More 

    Gene Full Name

    activating transcription factor 2

    Gene Summary

    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]

    More 

    Molecular Weight(MW)

    55KD

    Cellular Localizatio

    Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus

    Application

    ·        

    WB

    Western blot analysis using ATF2 antibody against A549(1) cell lysate.

    ·        

    IHC

    Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using ATF2 antibody with DAB staining.

    ·        

    ICC/IF

    Immunofluorescence analysis of Hela cells using ATF2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

    Application Notes

    WB:1:200-1:2000
    IHC:1:200-1:2000
    ICC/IF:1:100-1:500

    Additional Information

    Form

    Liquid

    Storage Instruction

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

    Storage Buffer

    Purified antibody in PBS with 0.05% sodium azide.


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