|
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
CRAF
Raf-1
c-Raf
CMD1NN
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-RAF1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAF1
Gene Synonyms
NS5
Hide
Gene Full Name
Raf-1 proto-oncogene, serine/threonine
kinase
Gene Summary
This gene is the cellular homolog of
viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase
(MAP3K), which functions downstream of the Ras family of membrane associated
GTPases to which it binds directly. Once activated, the cellular RAF1 protein
can phosphorylate to activate the dual specificity protein kinases MEK1 and
MEK2, which in turn phosphorylate to activate the serine/threonine specific
protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of
cell physiology and play an important role in the control of gene expression
involved in the cell division cycle, apoptosis, cell differentiation and cell
migration. Mutations in this gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane,
Mitochondrion, Nucleus
Application
ICC/IF:1:100-1:500
CRAF
Raf-1
c-Raf
CMD1NN
·
IHC
Immunohistochemical analysis of paraffin-embedded colon cancer tissues using RAF1 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using RAF1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using RAF1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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