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    产品展厅
    Anti-GSTM1 antibody
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM641708
    • 发布日期: 2024-09-12
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM641708
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口

    Product Profile

    Product Name

    Anti-GSTM1 antibody

    Antibody Type

    Primary Antibodies

    Immunogen

    Polypeptide

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Application

    ELISAICC/IFIHCWB

    WB:1:200-1:2000
    IHC:1:200-1:2000
    ICC/IF:1:100-1:500

    Species Reactivity

    HumanMouseRat

    Concentration

    1mg/ml

    Purification

    Protein A

    Target Information

    Gene Symbol

    GSTM1

    Gene Synonyms

    MU
    H-B
    GST1
    GTH4
    GTM1
    MU-1
    GSTM1-1
    GSTM1a-1a
    GSTM1b-1b

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    Gene Full Name

    glutathione S-transferase mu 1

    Gene Summary

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

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    Molecular Weight(MW)

    26KD(Observed:55KD)

    Cellular Localizatio

    Cytoplasm

    Application

            

    WB

    Western blot analysis using GSTM1 antibody against Cos7(1),Hela (2),Hepg2,A431(4) cell lysate.

    ·        

    IHC

    Immunohistochemical analysis of paraffin-embedded liver cancer tissues using GSTM1 antibody with DAB staining.

            

    ICC/IF

    Immunofluorescence analysis of C2C12 cells using GSTM1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin

    Application Notes

    WB:1:200-1:2000
    IHC:1:200-1:2000
    ICC/IF:1:100-1:500

    Additional Information

    Form

    Liquid

    Storage Instruction

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

    Storage Buffer

    Purified antibody in PBS with 0.05% sodium azide.



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