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    产品展厅
    Anti-FLT3 antibody
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM641708
    • 发布日期: 2024-09-14
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM641708
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口

    Product Profile

    Product Name

    Anti-FLT3 antibody

    Antibody Type

    Primary Antibodies

    Immunogen

    Polypeptide

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Application

    ELISAICC/IFIHC

    IHC:1:200-1:2000
    ICC/IF:1:100-1:500

    Species Reactivity

    HumanMouseRat

    Concentration

    1mg/ml

    Purification

    Protein A

    Target Information

    Gene Symbol

    FLT3

    Gene Synonyms

    FLK2
    STK1
    CD135
    FLK-2

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    Gene Full Name

    fms related receptor tyrosine kinase 3

    Gene Summary

    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

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    Molecular Weight(MW)

    113KD

    Cellular Localizatio

    Endoplasmic reticulum

    Application

    ·        

    IHC

    Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using FLT3 antibody with DAB staining.

    ·        

    IHC

    Immunohistochemical analysis of paraffin-embedded breast cancer tissues using FLT3 antibody with DAB staining.

    ·        

    ICC/IF

    Immunofluorescence analysis of Hela cells using FLT3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

    Application Notes

    IHC:1:200-1:2000
    ICC/IF:1:100-1:500

    Additional Information

    Form

    Liquid

    Storage Instruction

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

    Storage Buffer

    Purified antibody in PBS with 0.05% sodium azide.


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