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    产品展厅
    p-CREB-2 Antibody (Ser 245)
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM641708
    • 发布日期: 2024-09-14
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM641708
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口

    Product Profile

    Product Name

    p-CREB-2 Antibody (Ser 245)

    Antibody Type

    Primary Antibodies

    Modification Notes

    Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular cis-acting promoter and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding proteins have been identified within the ATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucine zipper dimerization and basic DNA binding domains but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins appear capable of binding CRE in its homodimeric form, certain of these also bind as heterodimers, both within the ATF/CREB family and even with members of the AP-1 transcription factor family.

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Applications

    IFIHC

    recommended for detection of Ser 245 phosphorylated CREB-2 of h origin by IF and IHC(P):

    Species Reactivity

    HumanMouseRat

    Concentration

    1mg/ml

    Purification

    Affinity purified

    Target Information

    Alternative Names

    epitope corresponding to phosphorylated Ser 245 of CREB-2 of human origin

    Tissue Specificity

    epitope corresponding to phosphorylated Ser 245 of CREB-2 of human origin

    Database Links

    Entrez Gene

    468

    Application

    ·        

    Application

    Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue extract showing nuclear localization.

    Application Notes

    recommended for detection of Ser 245 phosphorylated CREB-2 of h origin by IF and IHC(P):

    Additional Information

    Form

    Liquid

    Storage Instructions

    For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.

    Storage Buffer

    phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


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